Biology Pacing Guide:

1st Semester

Unit Name (pacing guide doesn’t include testing days and alternative scheduling)

Essential Knowledge (Know)


General Knowledge


Suggested Activities/ Labs/Demos (Do)

Advanced/Extended List

Textbook Chapter(s)

Unit 1: Scientific Method

(2 weeks)

-Hypothesis vs. Theory

- Variables – (Independent, dependent, standardized)

-Control group/setup

-characteristics of life

-Calvin & Hobbes

-Alien Activity

-Sow Bug

-living or not living


Ch 1

Lab Skills (on-going)

Lab Reports (technical writing)


-microscope skills

- Analyzing data from a lab (ex. calculate a mean from a set of data)


-Data Tables

-Graphing (Excel)

-measuring cell size (drawing)

-Kingdom survey of cells


Unit 2:

Cell Chemistry (part 1)

(1 week)

-Chemical Bonding (ionic, covalent, polar-covalent, hydrogen)

-atomic structure (+isotopes, ions)

-properties of water


-basic chemistry knowledge sheet


-water activity

-pH lab

-(Origins video)

-BTB Demo

-Big Bang

-Van der Waals



Ch 2

Cell Chemistry (part 2)


(1.5 week)

-Function of 4 biomolecules (proteins, carbs, lipids, nucleic acids)

-structure of 4 biomolecules (monomers & polymers)

-building biomols

-identifying organic compounds lab (& extension activities)


-dehydration/ condensation


-abiogenesis (Miller & Urey ) (or use in Evolution unit)


Cell Chemistry (part 3)

(1.5 week)

-enzymes are biological catalysts

-activation energy

-lock and key hypothesis (enzyme – substrate)

-bean juice lab

-denaturation ( effect of pH, temperature on enzymes)

-energy diagrams (endergonic and exergonic)


Unit 3:

Cell Biology (part 1)


(1 week)

-Difference between prokaryotes and eukaryotes (membrane bound organelles)

-virus (non-living organism)


-plant vs. animal cell

-cell city

-cell presentation (jigsaw)


-(pink gel-o)

-Kingdom activity (survey of organisms)

-endosymbiotic theory

-binomial nomenclature

-surface to volume ratio

Ch 7

Cell Biology (part 2)


(1.5  weeks)

-cell membrane is selectively permeable

-membrane is lipid bilayer

-fluid mosaic



-phospholipids (hydrophobic tails/ hydrophilic heads)

- other molecules associated with the membrane


Cell Biology (part 3)

 (included above)

-passive transport vs. active transport





-dialysis tubing transportation demo

-what’s up doc

-egg membrane transportation




-receptor mediated

-facilitated diffusion (protein channels)

-pumps (carrier/gated proteins)


Unit 4:

DNA (part 1)


(1 week)




-structure (double helix, 4 nucleotides,

-modeling DNA activity (paper, arts and crafts)

-Strawberry DNA

-Video: Photo 51

-DNA Video series


-sizes of E. coli


-purines and pyrimidines


Ch 12

DNA (part 2)


(1 week)

- DNA replication from template/ original strands (Semi-conservative replication)

-Chargaff’s rules

-hydrogen bonding

-origin of mutations

-DNA replication cartoon

-replication enzymes

-Okazaki fragment

- types of mutation

-Meselson-Stahl experiment


DNA (part 3)

(1 week)

-Central Dogma – protein synthesis (DNAà RNAàProtein)



-3 types of RNA

-codons (including reading chart)

-Hemoglobin activity

-paper chain transcription & translation




-types of mutations

-bacterial transformation

-gene expression (operons)


Unit :


(optional: 0.5 week)


-cell cycle

-phases of mitosis

-chromosome structure

-onion root tip lab

-mitosis flip book

-cancer (mutations)


-HOX Genes

-surface to volume ratio

Ch 10

Unit 5:

Cellular Respiration


(1.5 weeks)

Sugar + oxygen à energy + carbon dioxide + water


-mitochondrial structure

-aerobic (glycolysis, Krebs, electron transport chain-generalities)

-BTB Respiration Activity (in text) Yeastie Beasties

-BTB Demo

-anaerobic and fermentation

-NADH, etc

-FAD, etc

-ATP synthase (chemiosmosis)


Ch 9

Unit 6:


 (1.5 weeks)

Carbon dioxide + water + sun à sugar + oxygen

-chloroplast structure

-Light dependent reactions

-Calvin Cycle

-leaf disk assay

-paper chromatography demo

-color of photosynthesis

-membrane structure of thylakoids




Ch 8

 2nd Semester

Unit Name (common pacing guide does not include testing days and alternative scheduled days)

Essential Knowledge (Know)


General Knowledge


Suggested Activities/ Labs/Demos (Do)

Advanced/Extended List

Textbook Chapter(s)

Unit 7:

Body Systems

(part 1)


(1 week)

Homeostasis is maintaining a stable internal environment

-positive (shock, clotting and child birth)  and negative feedback loops (thermostat building or person)

-thermoregulation lab


-menstrual feedback loop

Ch 35

Body Systems

(part 2)


(1 week)

Circulatory system is central system for transporting nutrients and wastes (including gases)


-red blood cells

-blood flow through heart


-gas exchange



-Hemo the Magnificent video

-diagram of heart

-lymphatic (thoracic duct)

Ch 37

Body Systems

(part 3)


(2 weeks)

Nonspecific vs Specific immune response (3 levels)

-White blood cells

- 3 levels: skin, inflammatory and specific immune response (general)

-antibodies, antigens



-Osmosis Jones video

-pink disease activity (disease transmission)

-immune systems cartoon activity


-integumentary system

-inflammatory response (detailed)

-B-cells, T-cells, etc.




Ch 40

Body Systems

(part 4)


(1 week)

Neurons quickly relay body responses (homeostasis)

-structure of neuron

-nerve impulse (general)

-reflex lab

-endocrine system (slow relay of body responses-hormones -menstrual feedback loop)

-electrochemical nature of a neuron

-brain & drugs


Ch 35


(1 week)




-UR in trouble



Ch 38

Unit 8:


(part 1)


(1 week)


(Optional plant unit 1 week)

Meiosis halves the number of chromosomes  (generates haploid gametes)


-gametes haploid,

-diploid, zygote

-meiosis flipbook activity

-meiosis activity

-slide show

-(Wisconsin fast plants- monohybrid cross)

-spermatogenesis, oogenesis,

-chromosomal mutations


-(Plant Unit to grow Fast plants)

Ch 11, 14


(part 2)


(2 weeks)

Simple dominance and Segregation – (solve a simple monohybrid Punnett square)

-independent assortment (dihybrid cross)


-genotype (genes, traits and alleles)



-punnett square problems

-corn activity

-pedigree activity

-make a baby lab

-Gizmo – simple mouse house


-sponge bob worksheet






-incomplete dominance

-types of mutations



Unit 9:


(part 1)


(2 weeks)

Natural Selection acts on phenotypes


-Darwin’s theory of evolution


population genetics

-founder effect, genetic drift



-natural selection of forks and beans

-breeding bunnies lab

-peppered moth lab

-Evolution video series

-Who’s on First activity

-(Great Fossil Find Activity)



-lyell and hutton

-recessive lethal


-bottleneck event

-HOX genes

-micro (mutations) vs. macro (speciation) evolution

-big bang (Miller and Urey)

Ch 15-17


(part 2)



(1 week)


-Out of Africa model

-differentiate between different species


-Evolution video series

-lengthy relationships activity

-how tall were they activity

-hominid skull lab

-What does T-Rex taste like activity


-multiregional model of human evolution


Unit 10:

Biotechnology (forensics)


(1 week)

Analyze a DNA fingerprint



-DNA fingerprinting -crime scene (bio-rad)

-DNA to the Races activity

-Mix up at the Hospital activity

-OJ Simpson video

-restriction enzymes




(1 week)



-(Pickled Critters of the animal kingdom)

-(Dichotomous keys)





Unit 11:


(2 weeks)


-Analyzing changes in ecosystems

-energy flow

-food web/pyramid


-biome activity (design an ecosystem, biome vacation web sites, survivor)

-cycles of matter